nūhou

ʻO ka hoʻohuli ʻana o Splanchnic (me ka hoʻohuli ʻana i ka splanchnic holoʻokoʻa [dextrocardia] a me ka hoʻohuli ʻana o ka splanchnic partial [levocardia]) he ʻano ʻino ʻole o ka ulu ʻana o ka hānau ʻana ma ke ʻano o ka hāʻawi ʻana i ka splanchnic i nā maʻi e kūʻē i ko ka poʻe maʻamau. Ua ʻike mākou i ka piʻi nui ʻana o ka nui o nā hihia visceral inversion fetal i hoʻopaʻa ʻia e ka ultrasound ma kā mākou haukapila i kekahi mau mahina ma hope o ke kāpae ʻana i ke kulekele "zero clearance" o COVID-19 ma Kina.

Ma ka nānā ʻana i nā ʻikepili lapaʻau mai ʻelua mau kikowaena obstetric ma nā ʻāpana like ʻole o Kina, ua hoʻoholo mākou i ka ulu ʻana o ka fetal visceral inversion mai Ianuali 2014 a Iulai 2023. I nā mahina ʻehiku mua o 2023, ʻo ka hanana o ka inversion kūloko (maʻamau prenatal ultrasonography a me ka hoʻomaʻamaʻa ʻana ma kahi o 20 a 24 mau pule ma waho o ka hoʻomaʻamaʻa ʻana i nā makahiki he ʻehā) ʻoi aku ka nui ma mua o ka awelika o ka makahiki 2014-2022 ma nā kikowaena ʻelua (Figure 1).

Ua piʻi ka nui o ka hoʻohuli ʻana i ka visceral i ʻApelila 2023 a noho kiʻekiʻe a hiki i Iune 2023. Mai Ianuali 2023 a Iulai 2023, ua ʻike ʻia he 56 mau maʻi splanchnosis (52 huina splanchnosis a me 4 splanchnosis hapa). Ua piʻi ka nui o nā maʻi SARS-CoV-2 ma hope o ka hoʻopau ʻana i ke kulekele "zero clearance" COVID-19, a ukali ʻia e ka piʻi ʻana o nā hihia inversion visceral. Ua manaʻo ʻia ua hoʻomaka ka piʻi ʻana o nā maʻi SARS-CoV-2 i ka hoʻomaka ʻana o Dekemaba 2022, ua piʻi ma kahi o Dekemaba 20, 2022, a hoʻopau i ka hoʻomaka ʻana o Pepeluali 2023, e pili ana i ka 82% o ka heluna kanaka o Kina. ʻOiai ʻaʻole hiki ke huki ʻia nā hopena e pili ana i ke kumu, ua hōʻike kā mākou ʻike i kahi pilina ma waena o ka maʻi SARS-CoV-2 a me ka fetal visceral inversion, kahi mea e pono ai.ao ana.

Hōʻike ka Kiʻi A i ka hōʻoia ʻana o ka hoʻohuli ʻana o ka fetal splanchnic ma nā kikowaena obstetric ʻelua mai Ianuali 2014 a Iulai 2023. Hōʻike nā kiʻi ma luna o ka pakuhi pahu i ka huina o nā hihia no kēlā me kēia makahiki. Ua hōʻike ʻia ka nui o nā hihia i kēlā me kēia 10,000 wahine hāpai i loaʻa i ka nānā ʻana i ka ultrasound. Hōʻike ʻo Figure B i ka nui o nā hihia i hoʻopaʻa ʻia o ka inversion visceral mai Ianuali 2023 a Iulai 2023 ma ka China Welfare Society International Peace Maternal and Child Health Hospital (IPMCH) ma Shanghai a me ka Hunan Provincial Maternal and Child Health Hospital (HPM) ma Changsha.

Hoʻopili ʻia ka hoʻololi ʻana o ka visceral me ka hāʻawi ʻana i ka hormone morphogenetic abnormal a me ka hoʻonohonoho ʻana i ka cilium dysfunction i ka wā hāpai mua o ka embryo hema-akau axis asymmetry. ʻOiai ke hoʻopaʻapaʻa mau nei ka hoʻouna ʻana o SARS-CoV-2, hiki i ka maʻi embryo i ka wā hāpai mua ke hoʻopilikia i ka hoʻomohala ʻana o ka fetal visceral asymmetrical. Eia kekahi, hiki i ka SARS-CoV-2 ke hoʻopili pololei i ka hana kikowaena kiko hema hema ma o kāna pane ʻana i ka maʻi maternal mediated, no laila ke keʻe nei i ka hoʻomohala asymmetrical visceral. I nā haʻawina e hiki mai ana, pono ka nānā hou ʻana e hōʻoia i nā ʻano abnormalities pili i ka dyskinesia ciliary mua i ʻike ʻole ʻia i ka prenatal genetic screening ʻaʻole kuleana no kēia mau hihia, a no ka loiloi i ka hana kūpono o nā mea kaiapuni i ka piʻi ʻana o nā inpositions visceral. Pono e hoʻomaopopo ʻia ʻoiai ua hoʻonui ʻia ka ulu ʻana o ka visceral inversion i ʻelua mau kikowaena obstetric ma hope o ka piʻi ʻana o ka maʻi SARS-CoV-2, ʻaʻole nui loa ka maʻi maʻi o ka visceral inversion.